ALPHY is an annual meeting dedicated to the field of Bioinformatics and Evolutionary Genomics (ALPHY = ALignments and PHYlogeny). The main goal of this meeting is to promote informal exchanges in this highly multidisciplinary field, and to encourage young scientists to present their work. ALPHY is a working group of the GDR BiMM (whose aim is to structure and lead the French bioinformatics research community).